Effects of Nicotine

Last activity on July 22, 2024


Nicotine Addiction

Nicotine binds predominantly to nicotinic acetylcholine (nACh) receptors in the CNS; the primary is the α4β2 nicotinic receptor in the Ventral Tegmental Area (VTA)

After nicotine binds to the α4β2 nicotinic receptor in the VTA, it results in a release of dopamine in the Nucleus Accumbuns (nAcc) which is linked to reward

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